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Yohannes Tesfaigzi, PhD

Dr. Tesfaigzi is a member of the faculty in the Pulmonary and Critical Care Medicine at Brigham and Women’s Hospital and Professor of Medicine at Harvard Medical School.  Dr. Tesfaigzi graduated in Molecular Biology from the University of Hohenheim, Stuttgart, in Germany and completed his fellowship in cell and molecular biology at University of California, Davis.  Over the past two decades, the Tesfaigzi laboratory has contributed to the identification of genes and biochemical interactions of proteins that are responsible for maintaining a constant number of cells in airway epithelia.  Based on mechanistic studies, peptides and small molecules have been discovered that are highly effective in reducing mucus-producing cells in animal models of chronic bronchitis and asthmatic bronchitis.  Current efforts are to test these drugs in patients with these debilitating diseases.  Dr. Tesfaigzi is author of over 140 original research publications; has served on grant review panels for more than 10 different organizations, including several branches of the NIH.

Professor of Medicine, Harvard Medical School

Director of Cigarette Smoke Exposure Laboratory, Brigham and Women’s Hospital

Airway Epithelia in COPD and Asthma

Effects of cigarettes smoke, wood smoke, viral and bacterial Infections, ozone on lung epithelia

MS, University of Hohenheim, Stuttgart, Germany

PhD, University of Hohenheim, Stuttgart, Germany

Postdoc, Department of Biochemistry, University of California Davis

National Institutes of Health

Pharmaceutical Companies

Yohannes Tesfaigzi, PhD
Pulmonary and Critical Care Medicine,
Brigham and Women’s Hospital

15 Francis Street
Boston, MA  02115
Phone: (617) 525 3480
E-Mail: ytesfaigzi@bwh.harvard.edu

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